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SAMe: your body makes this when the pathway is fed correctly (Steps 1-4 on the Map)
USA 110 , 46224627 (2013)
2013;8(6):e67081
In a study performed to dissect the role of mGlu2 and mGlu3 receptors in the endogenous control of inflammatory pain, mice lacking mGlu2 receptors showed amplification of pain in the second phase of the formalin test, which reflects the development of nociceptive sensitization in the spinal cord [165]
