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GSH accounts for about 95% of the total non-protein thiols within cells, with intracellular concentrations ranging from 0.5 to 10 mM, far surpassing the levels of free cysteine (3-4)

Common signs may include lethargy, loss of appetite, and reduced weight gain

Among them the genes highly expressed in the resistant cells include cytochrome oxidase I, ribosomal protein 28S, elongation factor 1 , -enolase, stathmin and HSP70