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Kim JH, Lee J, Jeong H, Bang MS, Jeong JH, Chang M (2021) Nordihydroguaiaretic acid as a novel substrate and inhibitor of catechol O -methyltransferase modulates 4-hydroxyestradiol-induced cyto- and denotoxicity in MCF-7 cells
doi: 10.7860/JCDR/2017/26106.10428, 53

doi: 10.1093/jn/138.2.297

By optimizing the DAR, the conjugate can achieve an ideal balance between tumor-targeting potency and minimizing systemic toxicity (110)
