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Description
We generated a PRISMA diagram to describe the flow of information through the processes of identification, screening, and including records in this literature review, as shown in Figure 1 [23,24]
Apoptosis Initiation: Once liberated, p53 translocates to the mitochondria and activates BAX/BAK, triggering intrinsic apoptosis (cell death) specifically in the senescent cell
Another possible cause is a disordered immune system
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