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Mild: Appetite loss, upset stomach, diarrhea, constipation, rash

Inhibitors of the 26S proteasome (e.g., proteasome inhibitor 1 and lactacystin) blocked CDO degradation in Cys-deficient cells but had little or no effect on CDO concentration in hepatocytes cultured with excess Cys in which CDO concentration was already elevated

Therefore, accurate detection and diagnosis of fibrosis in the lung is highly recommended for the proactively clinical treatment as early as possible to circumvent potential respiratory failure and mortality

DSF has been used to treat alcohol dependence since 1947 ( In the last 40 years, the anticancer effects of DSF have been discovered in vitro and in cancer xenografts (Paranjpe et al., 2014)