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J Bacteriol 205:e0046322 Kurniyati K, Chang Y, Liu J, Li C (2022a) Identification and characterization of the alternative sigma(28) factor in Treponema denticola

B.N., A.C., J.D., A.S.M., I.G., J.O., Y.M., A.A., A.K

FIGURE 4 Genetic skin disease Ichthyosis is a group of genetic dermatoses with common clinical manifestations including generalized dry skin, erythema, desquamation, hyperkeratosis, and skin inflammation (Takeichi and Akiyama, 2016)

That outcome would move GHK-Cu off Category 1, likely toward Category 2 or the do-not-compound list
