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This decrease in NLR suggests a reduction in systemic inflammation, which could lead to better skin health outcomes

In terms of anti-inflammatory effects, it suppresses the production of pro-inflammatory cytokinesincluding TNF-, IL-1, and IL-6which are crucial contributors to the chronic inflammatory milieu in IPF (Jin et al., 2019)

10.1038/s41586-019-1654-9 Nature 70 KelleyK

Minocycline reduced microglial activation in human TBI patients but also increased neurofilament light, a marker of neurodegeneration in humans (142)