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nadph glutathione u87 cells Disruption of homeostasis by total flavonoids from Adinandra nitida Merr. ex Li leaves triggers ROS-dependent p53 activation leading to apoptosis in non-small cell lung cancer Ferroptosis as a therapeutic target
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Together they rebuild, grow, and protect neural tissue from three independent angles

Rodrigues, Dania C

doi: 10.1208/s12249-022-02259-z

A limitation to the therapeutic potential of the senolytic pan-BCL inhibitors ABT-263/ABT-737 is their tendency to cause severe thrombocytopenia(Schoenwaelder et al., 2011)
