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The quadruplet regimen Dara-VRd (Daratumumab + Bortezomib + Lenalidomide + Dexamethasone) has recently shown superior response rates, higher minimal residual disease (MRD) negative rates, and improved progression-free survival in newly diagnosed multiple myeloma patients

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It is central to: Detoxification: Neutralizing free radicals and heavy metals Immune defense: Maintaining lymphocyte and macrophage function Redox homeostasis: Regulating disulfide bonds and antioxidant recycling Cellular repair: Protecting lipid membranes and mitochondrial DNA Despite its significance, traditional glutathione supplements face major limitations: Poor intestinal absorption Rapid breakdown into constituent amino acids Minimal rise in systemic glutathione levels Weak clinical outcomes This gap between glutathiones potential and its real-world efficacy is what motivated the move toward liposomal delivery systems