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Description
Its the swelling, heat, sweating, pain, and increased blood flow that often surrounds the site of injury

[DOI] [PubMed] [Google Scholar] 174.Jevtovic-Todorovic V, Guenthner TM

This process of antibody evolution and maturation continues in germinal centres for up to 6 months after initial antigen exposure 12,143

You might notice mild redness or soreness at the injection site
