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Additionally, proteomic analysis demonstrated that chemical activation of CD4 + T cells by the drug-like ClpP agonist NCA029 inhibits OXPHOS and Th17 cell differentiation in vitro, thereby alleviating symptoms of IBD [115]

Wendisch VF, de Graaf AA, Sahm H, Eikmanns BJ (2000) Quantitative determination of metabolic fluxes during coutilization of two carbon sources: comparative analyses with Corynebacterium glutamicum during growth on acetate and/or glucose

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