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3.2.2 Preclinical studies Several animal studies have also outlined the neuroprotective effects of SF in PD
Patients can present as heterozygotes with only one gene encoding for an abnormal enzyme, or as a homozygote with both genes encoding for the defective enzyme
Sex difference Sex difference may also influence the effect of exercise
Expression of the considered ThDP-dependent enzymes and isoenzymes in enterocytes (Figure 1B) underscores both the common and isoenzyme-specific dependence of gastrointestinal metabolism on thiamine
