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Lipid location and overall structure details MGST1 molecules form two trimers centered on the three-fold axes of the p6 unit cell (Supplementary Fig
From a chemistry perspective, pH is especially important because it can alter the ionisation state of acidic and basic amino acid side chains
The dose-response curve between 8 and 12 mg shows diminishing returns, meaning 10 mg captures most of the benefit while potentially reducing some of the dose-related side effects seen at 12 mg
