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This variability may be due both to the large size of the NF1 gene, which lends itself to a greater frequency of mutations, as well as the large number of possible means in which the function or amount of neurofibromin produced may be affected [16]
10.2165/11898640-000000000-00000 58 ShanM.YuS.YanH.ChenP.ZhangL.DingA
Case 3 A 57-year-old man, former smoker, with a clinical history of tracheotomy in 2005 due to long-term orotracheal intubation
As the brain ages, it loses many of its neurites, which leads to reduced efficacy and slowing of most cognitive processes
