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Description
The primary outcome measure was the ACR20 response at 24 weeks, with ACR50/70/90, DAS28, EULAR response criteria, and time to ACR20 as secondary outcome measures

Critically, this symbiosis fuels the high oncogenic biosynthetic and bioenergetic demand of the growing tumor, which can then mediate chemoresistance [17, 18]

Reactive oxygen species: Metabolism, oxidative stress, and signal transduction

Li F, Xie Y, Yang X, Zhang Y, Cheng B, Shan A