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8 Conclusion The convergence of circadian biology and aging research reveals time not merely as a backdrop but as a dynamic biological force, where Kronos , that represents the linear progression of age, and Kairos , the opportune moment dictated by biological rhythms, co-determine the trajectory of health and disease
Shailajan Sunita M, Sasikumar

It is critical to recall that all of this data comes from preclinical models (rodent, porcine, in vitro) and limited case studies

In these cases calcium uptake, PS exposure and abnormal alterations in cell volume, membrane architecture, as well as redox balance may play a much more important role