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Physico-Chemical Soc
Furthermore, it is potentially benefiting the gut lining and offering protection and healing for the digestive system
Immediate medical intervention is essential to prevent lasting harm
Gemtuzumab ozogamicin, the first approved ADC, primarily utilizes the acid-sensitive cleavage of the hydrazone linker to release cytotoxic agents, whereas the disulfide bond cleavage predominantly occurs during the intramolecular activation of N -acetyl--calicheamicin, which serves to maintain its molecular conformational stability rather than functioning as a release mechanism for the linker [124]
