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It represents categorising people into subpopulations and identifying specific treatment options that benefit those populations (Woodcock, 2007)

Furthermore, there is a transition of mouse de novo methyltransferase expression from Dnmt3b to Dnmt3a during neural progenitor cell development [50], suggesting that particular DNMTs play a role in neuronal function at specific times over neuronal development and maturation

These manifestations stem from mitochondrial dysfunction, often caused by mutations in genes related to mitochondrial function, leading to impaired energy production and widespread neurological and metabolic abnormalities

Quant EC, Jeste SS, Muni RH, et al