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[PubMed] [Google Scholar] 15.Crew KD, Brown P, Greenlee H, Bevers TB, Arun B, Hudis C, McArthur HL, Chang J, Rimawi M, Vornik L, Cornelison TL, Wang A, Hibshoosh H, et al

Immunity 2012;36:4354

In this paper, we offer substantial evidence showing that these interactions can increase the risk of serious cardiac, hematologic, immunologic, and neurological AEs, especially in vulnerable individuals

The retatrutide onset timeline varies between individuals but most report clear effects by the 2-4 mg dose range
