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15 Meanwhile, chronic inflammation driven by intestinal permeability and autoimmunity, and other factors like processed food16and poor sleep, 17 may suppress thyroid activity

Reactive oxygen species have been determined to be critical inducers of various forms of cell death, which are collectively termed oxidative cell death [5]

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Accordingly, the expression changes of L2HGDH by sg L2HGDH , L2HG treatment, or L2HGDH OPT led to decreased or increased DNA hydroxymethylation in the CBS promoter CpG island (Fig
