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The pro-apoptotic and anti-proliferative activities of eckol (a marine-derived phlorotannin) are demonstrated by the upregulation of Bax, caspase-3, and caspase-9 expression, alongside downregulation of Bcl-2 expression through in vivo experiments ( Galangin has been reported to regulate key apoptotic markers in a concentration-dependent manner in ovarian cancer cells

This lipid-lowering effect may be related to its antioxidant ability

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Although in cognitively healthy individuals differences in BBB uptake have been observed with APOE genotypes as early as in individuals in their 30s (Yassine et al., 2017) in mice older ages may be required for such disturbances to occur (Alata et al., 2015)
