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Its role appears modulatory rather than suppressive, supporting coordinated neural and endocrine timing rather than inducing forced sleep states

Metabolite-to-parent AUC inf (AUC inf,m /AUC inf,p ) ratios for midazolam and dextromethorphan were calculated to compare the relative abundance of metabolite to parent drug in the circulation

They shield neural circuits from chronic stress, reduce maladaptive stress responses, and aid in reestablishing normal hypothalamic signaling

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