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Effectiveness of hydrolyzed collagen peptide injection for the treatment of collateral ligament pain: A randomized controlled trial
Nicotinamide phosphoribosyltransferase (NAMPT) is the key rate-limiting enzyme in nicotinamide adenine dinucleotide (NAD) synthesis, influencing cellular metabolism by regulating NAD regeneration [145]

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123 They further identified that the risk alleles, rs3761581G and rs2235312T were related to lower levels of apelin expression and nitrite, highlighting the complex interplay of genetic factors in HAPE pathogenesis
