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No abnormalities were observed in hematological or biochemical indices, urinalysis, or behavioral and ophthalmic assessments

Figure 1 Larger molecules, such as proteins and bacterial products, penetrate by the mechanism of receptor-mediated endocytosis, which implies the invagination of the plasma membrane and the subsequent formation of vesicles, as a consequence of proteins or peptides binding to specific cell surface receptors (148)

Altogether these data suggest that gut microbiota is crucial in preserving the integrity of the IEB, thus preventing the systemic spreading of potentially harmful antigens

doi: 10.18632/oncotarget.2661