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The microbiota also ferments soluble fibers and produces short-chain fatty acids, which promote the regeneration of colonocytes and may improve recovery from diarrhea (202)

Multi-disciplinary treatment may be required to improve cancer cachexia, including the use of oral nutritional supplements, L-carnitine, thalidomide, n-3 fatty acids, and megestrol acetate, as was shown in a five-arm randomized clinical trial [46]

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These comparator categories were prespecified to keep comparisons clinically meaningful and to avoid pooling different control types that could blur ALCs added effect
