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Assess your tolerance before increasing dosage beyond 1,500 mg

Epub 2021 Dec 7

It must be specified that propolis is a product made by bees containing many substances that have useful properties for PD treatment: polyphenols (including flavonoids and resveratrol), cinnamic acid, caffeic acid, fatty acids, certain vitamins (E, C, B1, B2, and B6), and chemical elements (zinc, iron, calcium, sodium, potassium, magnesium, manganese, copper, iodine, nickel, titanium, cobalt, and silicon)

In the substrate oxidation stress test, the cells were prepared as above prior to the assay, and the cells were subjected to (in sequence, in final concentrations): (1) 0, 4 mM l-glutamine (Seahorse Bioscience, Billerica, MA, USA), 40 M Etomoxir (11969, Cayman Chemical, Ann Arbor, USA) or 3 M BPTES ((bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide)