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Crawford AA, Soderberg S, Kirschbaum C, Murphy L, Eliasson M, Ebrahim S, et al
Reduced CYP2C9 activity, caused by genetic variation in the CYP2C9 gene, increases systemic exposure to fluvastatin, which can predispose an individual to increased risk of fluvastatin-induced muscle-related adverse events
What the Published Research Shows: Specific Doses and Outcomes When examining human-equivalent dosing, researchers typically convert rodent study doses using established allometric scaling formulas
