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Furthermore, preclinical studies showed that juvenile stress increases hippocampal MR mRNA levels and anxiety-like behavior in adulthood [23]
However, the alteration of phospholipid metabolism in AD is also observed in the blood, thus encouraging discovery studies for blood-based lipid markers (273, 290)
Myotubes could be induced to hypertrophy by the PI3K/Akt pathway, which increases protein synthesis and blocks the up-regulation of MAFbx and MuRF1 that occurs during muscle atrophy [54, 59]
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