glutathione peroxidase glial cells and parkinson& 39 peroxidase-1 (GPX-1)–mediated protection of SK-N-MC Glial cells improve Parkinson's disease
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In endosomes, Fe 3+ is reduced to Fe 2+ by STEAP3 (STEAP3 metalloreductase), and then Fe 2+ is released into the cytosol through divalent metal transporter 1 (DMT1) [84]
This is then regenerated into BH4 with the help of 5-MTHF from the folate cycle
