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However, another study from Japan showed that the eradication effectiveness of first-line triple therapy with amoxicillin, clarithromycin, and vonoprazan decreased with age, possibly due to reduced gastric acid secretion in older patients, reducing the need for maintenance therapy with vonoprazan (Kusunoki et al., 2019)
Therefore, the intracellular levels of GSH are regulated by the negative feedback of GSH itself on the GCL enzyme (Figure 3)
However, some can interact with medications or have side effects at very high doses
doi: 10.1136/jcp.2006.042408 [DOI] [PMC free article] [PubMed] [Google Scholar] 537
