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Discussion There were two key findings in this study of older HIV-infected patients: 1) deficient intracellular GSH synthesis and decreased GSH regeneration contribute GSH deficiency and can be corrected with short-term cysteine plus glycine supplementation and 2) correcting GSH deficiency was associated with marked improvements in mitochondrial fuel oxidation in the fasted and fed states, insulin sensitivity, muscle strength, and body composition

This makes them suitable for daily supplementation for most adults

human evidence does not exist, so these are hypotheses rather than expected outcomes

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