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[DOI] [PubMed] [Google Scholar] [124].Shin EJ, Chung YH, Sharma N, Nguyen BT, Lee SH, Kang SW, Nah SY, Wie MB, Nabeshima T, Jeong JH, Kim HC, Glutathione peroxidase-1 knockout facilitates memory impairment induced by beta-amyloid (142) in mice via inhibition of PKC betaII-mediated ERK signaling

Ayoub SS, Flower RJ (2019) Loss of hypothermic and anti-pyretic action of paracetamol in cyclooxygenase-1 knockout mice is indicative of inhibition of cyclooxygenase-1 variant enzymes

Supplementing with cysteine to increase glutathione is therefore of little use, except in a few severe and limited cases mainly used in clinical settings

They range from some localized benefits to systemic benefits