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Healthy, dividing cellswhich rely less on the FOXO4p53 survival mechanismare spared
[DOI] [PubMed] [Google Scholar] 47.Visanji N
Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs
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