recombinant igf-1 lr3 IGF-1LR3 Heterologous expression of IGF-1/LR3 IGF-1

The higher dose (50 mg/kg) showed superior effects, reducing ALT and AST by 74.7% and 70%, respectively, while increasing albumin by 155.6% compared to the TAA group, bringing these parameters closer to normal values (Figures 1AC)

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Studies have shown that melatonin can synchronize the clock machinery in healthy and damaged cells to upregulate or downregulate specific clock genes to sustain optimal physiology in cells (67, 68)

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