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Atherosclerosis is a systemic disease, the main cause of heart disease, is associated with hyperlipidemia and lipid oxidation and has always been a common single leading cause of death in well-developed countries

However, it is important to speak with a healthcare professional before starting supplementation to ensure it is appropriate for the individual context

Moreover, synbiotics have been reported to improve gut integrity via SCFA production, by which inhibiting the TLR4LPS complex-triggered proinflammatory cascade, hampering proinflammatory cytokine signaling pathways, such as nuclear factor kappa B (NF-B), thereby decreasing insulin resistance (34)