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P = 0.001) and GSH ( F = 3.572
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The lobular distribution of hypertrophic hepatocytes is classically considered to be centrilobular (Figure 3) for many microsomal enzyme inducers

The study also found increased expression of PPARalpha and PGC1alpha, transcription factors involved in fat oxidation and mitochondrial biogenesis

The initially increased end- diastolic and end-systolic volumes were also significantly reduced in the L-carnitine treated patients