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IS, MM, IHS, XL, SJ, JW, PA, and MA contributed reagents, materials, and analysis tools
2-Deoxy-D-glucose (2DG), a glycolysis inhibitor, can competitively bind to hexokinase to inhibit glycolysis, subsequently reducing the inflammatory response triggered by M1 macrophages (146) and simultaneously enhance the tolerance of macrophages to endotoxin (147)
Imatinib, also a TK inhibitor, will be compared to methylprednisolone in a short-course proof-of-concept study
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