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Intriguingly, there is also a cytosolic form of aconitase, and when it loses its ISC, it becomes iron regulatory protein 1 that acts as an important regulator of cellular iron uptake and storage [33]

Cancer Cell 20 , 200213 (2011)

This implies that IR is linked to a higher metabolic risk and may be particularly noticeable in teenage PCOS patients who have severe irregularities in their menstrual cycles, such amenorrhea

Abstract Given the unique physiological and pathological characteristics of the lung, the direct, inhalable route is more conducive to pulmonary drug delivery and disease control than traditional systemic drug delivery, significantly circumventing drug loss, off-target effects, systemic and organ toxicity, etc., and is widely regarded as the preferred regimen for pulmonary drug delivery