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Its approval was based on positive results from the LUMINOSITY trial (NCT03539536)

Men with voided volume less than 150 mL were more likely to have Hunner lesions than those with voided volume exceeding 150 mL

In addition, ROS can activate p38 MAPK and FOXO1 pathways, leading to trophoblast apoptosis and downregulation of P synthases expression

Water dynamics in the hydration shells of biomolecules
