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Description
Lyme disease complicated by the Jarisch-Herxheimer reaction

A characteristic feature of the disease is the need to take a specific intoxicating substance causing psychological and physical addiction

2.2.1 Oxidative stress and mitochondrial dysfunction METH significantly increases the production of ROS and reactive nitrogen species, overwhelming antioxidant defenses in neurons

Ferroptosis is a way to regulate CD caused by iron overload and reactive oxygen species (ROS)-dependent lipid peroxides accumulation, with structural changes focused on mitochondria (Shojaie et al., 2020)
