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For instance, Jomova et al (177) demonstrated that an excess of copper ions led to the aggregation of fatty proteins and abnormal expression of Fe-S cluster proteins, resulting in protein toxic stress and cell death

In comparative studies, GHK-Cu demonstrates stronger collagen-stimulating activity and broader gene modulation scope than AHK-Cu, likely due to differences in copper binding affinity and cellular uptake kinetics

Current treatments for gastroparesis include prokinetic agents that target neurotransmitter systems within the ENS