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Elevated levels of pro-inflammatory cytokines from macrophages and other immune cells, such as TNF-, IFN-, IL-1, and IL-6, have been detected in patients with different types of hair loss, where they disrupt the follicular stem cell signaling and the follicle cycle [4, 25, 26]

HighAffinity Efflux Transport System for Glutathione Conjugates on the Luminal Membrane of a Mouse Brain Capillary Endothelial Cell Line (MBEC4). Journal of Pharmacology and Experimental Therapeutics 288: 198203

For at-home use, 0.250.5 mm is generally considered safe

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