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Practical Implications of No IGF-1 Elevation: The absence of IGF-1 stimulation makes AOD-9604 suitable for populations who need to avoid IGF-1 elevation, including individuals with personal or family history of hormone-sensitive cancers, those concerned about accelerated aging through growth pathway activation, people seeking fat loss without anabolic muscle-building effects, individuals who have contraindications to growth hormone therapy, and those undergoing screening or monitoring where IGF-1 elevation would be problematic

[DOI] [PMC free article] [PubMed] [Google Scholar] 318.Wang, D

External resources for tirzepatide and B12 research Clinical trial data for tirzepatide weight loss efficacy comes primarily from the SURMOUNT trial series published in The New England Journal of Medicine

You may feel a slight pinch or sting, but this should quickly subside