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omaveloxolone was also found to increase the expression of aminotransferases in cultured liver and skeletal muscle cell lines (Supplementary Fig

Notably, only TSA2 is constitutively induced

3 With elucidation of its mechanism, incidence, and impact on resistance to chemotherapy, interventions to decrease target concentrations of GSH may become part of future oncologic therapeutic regimens

Huang M, Lou D, Charli A, Kong D, Jin H, Zenitsky G, et al
