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Moreover, disulfiram (DSF) does not cause depletion of total GSH, but shifts the ratio of GSH/GSSG towards the oxidized state

Data are synthesized from clinical trials and categorized on a scale from 0 (no effect) to 5 (strong effect)

The high expression of ASCT2 enhances Gln uptake and metabolism, which activates the mTORC1 nutrition-sensing pathway (16)
