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This has proved to be an effective treatment for blepharitis, ocular rosacea, meibomian gland dysfunction, styes, chalazia, and dry eye by facilitating the ongoing flow of the oils from the meibomian glands

They are NAD+-dependent, meaning they require NAD+ to function

Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis