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BPC-157 upregulates VEGFR2 expression and promotes receptor internalization, triggering downstream phosphorylation of Akt at specific sites (Ser473 and Thr308)

Therefore, this inverse correlation is speculated to act as a compensatory mechanism to increase the effect of GABA on postsynaptic cells and return the circuitry back to homeostatic conditions [57, 62, 82]

Perperopoulou et al., 2017)