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The shared molecular binding of the brains vitamin B 12 carrier protein, known as transcobalamin 2 or TCN2, with the FDA-approved MS drug fingolimod provides a mechanistic link between B 12 signaling and MS, towards reducing neuroinflammation and possibly neurodegeneration said Chun

Insulin resistance and inflammation, linked with obesity, also appear to reduce sperm motility and increase DNA fragmentation in sperm cells

Dietary and Lifestyle Risk Factors Certain diets and lifestyle factors also increase the risk of B12 deficiency
