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The Foundation FAPESP did not influence in the design of the study and collection, analysis, and interpretation of data or the writing of the manuscript
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Brucein D, a naturally occurring quassinoid, enhances the sensitivity of pancreatic ductal adenocarcinoma (PDAC) cells to gemcitabine (GEM) by promoting the ubiquitin-proteasome-dependent degradation of NRF2 and suppression of the NRF2 signaling pathway [104]
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