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Post-translational modifications, such as nitration and phosphorylation, further enhance the tendency of alpha-synuclein to misfold and aggregate 7,36
In the metabolic formation, Hcy-thiolactone spontaneously reacts with protein lysine residues 12,13,16 and generates N-Hcy-protein
These genes are involved in detoxification processes and help protect cells against oxidative stress, inflammation, and mitochondrial dysfunction
Front Immunol (2019) 10:85
